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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNPC3 All Species: 30.61
Human Site: S447 Identified Species: 51.79
UniProt: Q96LT9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LT9 NP_060089.1 517 58575 S447 F G R Y V D F S S E T Q R I M
Chimpanzee Pan troglodytes XP_524780 517 58585 S447 F G R Y V D F S S E T Q R I M
Rhesus Macaque Macaca mulatta XP_001108341 447 50381 K407 F I G L P N E K A A T K A L K
Dog Lupus familis XP_547257 729 81274 S659 F G R Y V D F S S E T Q R I M
Cat Felis silvestris
Mouse Mus musculus Q3UZ01 514 57954 S445 F G R Y V D F S S E T Q R I M
Rat Rattus norvegicus Q4G055 515 58019 S446 F G R Y V D F S S E T Q R I M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509729 515 58068 S445 F G R Y V D F S S E T E R I M
Chicken Gallus gallus XP_422302 550 62756 Q480 F G R Y V D F Q S V L E R N M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001035019 505 56850 S432 Y G R Y I D I S S E E E R N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623250 403 46802 G364 M Q E G R M K G Q A F I T L Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783188 518 57780 T436 F G R Y V D W T S P L D K D M
Poplar Tree Populus trichocarpa XP_002325403 420 46033 G381 Y I F G S L F G S I D A A K S
Maize Zea mays NP_001132325 450 49544 V411 R M R G Q A F V T F P T V E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172394 442 48694 T403 M R G Q A F L T F P S V E V A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 83.1 66.1 N.A. 88.7 88 N.A. 72.1 66.9 N.A. 56.4 N.A. N.A. 33.4 N.A. 40.5
Protein Similarity: 100 99.8 83.3 68.1 N.A. 93.2 92.6 N.A. 82.7 78 N.A. 71.1 N.A. N.A. 48.5 N.A. 58.6
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 93.3 66.6 N.A. 60 N.A. N.A. 0 N.A. 53.3
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 100 73.3 N.A. 80 N.A. N.A. 6.6 N.A. 73.3
Percent
Protein Identity: 28 30.9 N.A. 32.8 N.A. N.A.
Protein Similarity: 42.5 47.7 N.A. 47.9 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: 20 26.6 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 8 15 0 8 15 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 65 0 0 0 0 8 8 0 8 0 % D
% Glu: 0 0 8 0 0 0 8 0 0 50 8 22 8 8 0 % E
% Phe: 65 0 8 0 0 8 65 0 8 8 8 0 0 0 0 % F
% Gly: 0 65 15 22 0 0 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 8 0 8 0 0 8 0 8 0 43 0 % I
% Lys: 0 0 0 0 0 0 8 8 0 0 0 8 8 8 8 % K
% Leu: 0 0 0 8 0 8 8 0 0 0 15 0 0 15 8 % L
% Met: 15 8 0 0 0 8 0 0 0 0 0 0 0 0 65 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 15 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 15 8 0 0 0 0 % P
% Gln: 0 8 0 8 8 0 0 8 8 0 0 36 0 0 8 % Q
% Arg: 8 8 72 0 8 0 0 0 0 0 0 0 58 0 0 % R
% Ser: 0 0 0 0 8 0 0 50 72 0 8 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 15 8 0 50 8 8 0 0 % T
% Val: 0 0 0 0 58 0 0 8 0 8 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 65 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _